Iyo Yakachengeteka Muscle Booster Supplement: Urolithin A (UA) Powder AASraw
MUTSVENE unoburitsa Cannabidiol (CBD) upfu uye Hemp Yakakosha Oiri muhuwandu!

Chimwe chezvinangwa zvikuru zvevanovaka muviri uye vatambi ndechekuwedzera mhasuru yakaonda uye kuvandudza toni, pamwe chete nesimba, remhasuru. Zvinogona kunetsa kuwana mhedzisiro iyi nekurovedza muviri kana zvirongwa zvekudzidzisa chete. Kuronga kwakasimba kwekudya, kushandiswa kweakakosha macronutrients, uye kushandisa mamwe pre-workout uye post-Workout yekuwedzera inodiwa kuti pave nekukura kwakakwana kwemhasuru munguva yakafanotarwa.

Kune nzira dzakawanda dzekuvandudza kukura kwemhasuru yako uye kuona shanduko huru mumutumbi wako, iyo inonyanya kukosha ndeyekudya mapuroteni akakwana. Kudya kweprotein nekudya kwega kwega kunogona kubatsira kukura kwemhasuru yako, sezvo maamino acids kubva kumapuroteni aya anobatsira kugadzirisa kukuvadzwa kwetsandanyama uye kuzadza zvitoro zveprotein mumamhasuru, mushure mekurovedza muviri kwakawanda. Carbs inofanira kudziviswa kazhinji, kunze kwekunge mushure mekurovedza muviri apo kukura kwemhasuru ndicho chinangwa.

Imwe nzira inokurumidza yekusimudzira kukura kwemhasuru ndiko kushandiswa kwe steroids. Vanowanzowana mukurumbira wakashata sezvo mamwe emhando dze steroid dzakarambidzwa kushandiswa nechero muumbi wemuviri kana mutambi nevakuru vanobatana. Nekudaro, kune akatiwandei mamwe marudzi akachengeteka uye ari pamutemo kushandisa, ayo akaonekwawo kuti anobatsira kuburikidza neakawanda zvidimbu zvezvidzidzo zvesainzi.

Steroids inogona kuiswa pamusoro, kana kutorwa muchimiro chepiritsi kana jekiseni, zvakananga mumhasuru. Chinangwa chema steroids ndechekuwedzera kukura kwemhasuru, nekudaro zvichikonzera kukura kwemhasuru asiwo kuwedzera simba remhasuru. Vavaki vemiviri vanoshandisa steroid vanoshuma kuvandudzwa mukusimba uye kutsungirira mujimu, izvo zviri zvechokwadi kuwedzera mukufarira steroid.

Urolithin A (UA) Poda - 01

Kuenzaniswa neSteroid, Ndezvipi Zvakanakira zveUrolithin A (UA)?

Kana rusarura rwakatenderedza steroid rwusina-kuisa kwauri uye uri kutsvaga imwe nzira, ipapo iyo Urolithin A kuwedzera zvingave zvakakodzera kutarisa. Urolithin A poda ine simba uye yakachengeteka tsandanyama inosimudzira, mabhenefiti ayo akatsigirwa nekongiri yesainzi humbowo. Mabhenefiti eiyi muscle booster akadzokororwa uye akaedzwa mune akawanda akasiyana zvidzidzo, uye imwe neimwe yakatsigira zvinofungidzirwa mabhenefiti. 

Iyo anabolic steroid iyo vatambi vanoshandisa inogona kuvandudza tsandanyama kukura zvakanyanya asi mhedzisiro yemishonga iyi, senge yakaderera testicular size nekuda kwe testicular atrophy uye infertility, inodarika zvikomborero zvemushonga. Ichi ndicho chikonzero zvakakosha kutsvaga dzimwe nzira, uye Urolithin A ine potency yakafanana kana yakawedzera, mukuenzanisa, iyo inovandudza kukura kwemisumbu. Nekudaro, mhedzisiro yeUrolithin A haina kana pedyo nekuve yakakomba semhedzisiro yesteroids.

Urolithin A chinhu chakachengeteka uye chinoshanda chekuwedzera chine anti-kuchembera, metabolic, neuroprotective, uye anti-obesity mabhenefiti. Zvinoenderana nezvidzidzo zvakaitwa kuongorora mabhenefiti ekuwedzera, yakachengeteka kuti ishandiswe nevanhu. Zvakare, hapana chakataurwa chetoxicity kana yakashata mhedzisiro yakataurwa, kusvika parizvino. Kushandisa chigadzirwa chakakodzera muchiyero chakakodzera kunogona kubatsira kuderedza njodzi yechero zvingangoita mhedzisiro zvakanyanya.

Urolithin A, kubvira kuwanikwa kwayo mu2000s, yakadzidzwa zvakanyanya nekuda kwemabhenefiti ayo akadai sekusimudzira tsandanyama uye kugona-kusimudzira kutsungirira. Nekudaro, kune akati wandei mamwe mabhenefiti ekomboni akawanikwa semhedzisiro yezvimedu zvetsvagiridzo, uye anotaurwa pazasi:

  • Kutarisira metabolic kusagadzikana

Pakuyedza kugona kweUrolithin A kuwedzera kutsungirira kune vakwegura, vatsvakurudzi vakawana kuti metabolite yakaderedza zvakanyanya kuwanda kweceramides uye acylcarnitine mumuviri. Izvi zvinowanzobatanidzwa mukukanganisika kwemetabolism inotarisa mitochondria. Saka zvakagumiswa kuti Urolithin A inogona kubatsira kubata mitochondrial metabolic kusagadzikana. 

  • Neuroprotective mhedzisiro

Nepo iyi bhenefiti yeUrolithin A yekuwedzera isinganakidze sekugona kwayo kuwedzera kukura kwemhasuru, yakakosha zvakaenzana. Maererano nekuongorora kwakaitwa pamhando dzemhuka, zvakaonekwa kuti kushandiswa kwemetabolite kwakavandudza zviratidzo zveAlzheimer's, kunyange zvazvo kutsvakurudza kwakawedzerwa kunodiwa kusati kwashandiswa senzira yekurapa.

  • Anti-obesity madhara

Urolithin A yakadzidzwa zvakare nekuda kwekubatsira kwayo kwemetabolism apo imwe yemabhenefiti yakawanikwa zvakangoitika panguva yeongororo yanga ichiitwa kuongorora kushandiswa kweUrolithin A yekuwedzera mukuvandudza kutsungirira kwemhasuru pakati pevakweguru. 

Mhuka dzemhando dzekudya dzakakora-mafuta kana HFD dzakadzidzwa sezvo dzakapihwa Urolithin A yekuwedzera. Urolithin A mune idzi mbeva dzakafuta yakakonzera kutsvukira kwewhite adipose tissue uyezve, Urolithin A yakasimudzira thermogenesis yebrown adipose tissue, kunyungudutsa mafuta. Urolithin A haingonyungudise mafuta chete asi yakawanikwawo kudzivirira kuwanda pakati pembeva dzaidyiswa HFD. Iyi metabolic uye anti-obesity mhedzisiro yeUrolithin A poda inogona kuvhura nyika nyowani yemikana uye mashandisiro eiyo metabolite.

Chii chinonzi Urolithin A (UA)?

Urolithin A inhengo yeorganic iyo inogadzirwa kubva ku ellagitannins neiyo microbiota muura. Urolithins ma polycyclic anonhuwirira makomisheni ayo ari metabolites akaumbwa kubva kune anotangira senge ellagic acid uye ellagitannins, anowanikwa mumichero yechisikigo senge pomegranate.

Pomegranate peel ine hupfumi mukati Urolithin B nepo Urolithin A isina chaiyo yekudya sosi. Pane kudaro, inoumbwa nekushandurwa kwematannins anowanikwa mumichero negut flora. Kuumbwa kwezvokudya zvekudya zve ellagitannins kunotaurwa mutafura iri pasi apa. Aya masosi ekudya anoita seasina kunanga masosi eUrolithin A, pamberi peane hutano gut microbiota ayo anokwanisa kuita shanduko.

Chikafu chinobva Ellagic Acid
michero 
Masango 150
Dema raspberries 90
Boysenberries 70
Cloudberries 315.1
mutamba 269.9
Raspberries 270
Ruva hudyu 109.6
Strawberries 77.6
Strawberry jam 24.5
Yero raspberries 1900
Nuts (mg / g)
Pecans 33
Walnuts 59
Zvinwiwa (mg / L)
Pomegranate muto 811.1
Cognac 31-55
Waini tsvuku-yemakore 33
Whisky 1.2
Mbeu (mg / g)
Dema raspberries 6.7
Tsvuku tsvuku 8.7
Boysenberries 30
Mango 1.2

Urolithin-A Inoshanda Sei Pakusimudzira Tsandanyama?

Urolithin A yatora nzvimbo ye steroid mumusika sezvo yakachengeteka uye ine simba mhasuru inosimudzira. Urolithin A vatengesi vanokurudzira kushandiswa kwechiwedzera ichi nekuda kwezvikomborero zvakawanda zvechigadzirwa, chinonyanya kukosha chiri kukura kwemhasuru. Simba retsandanyama, kukura, uye kutsungirira kunoenderana zvakanyanya nebasa remitochondrial mumaseru. Mitochondria ndiyo simba resero, uye ivo vane basa rekugadzira ATP, inova mari yesimba remuviri. 

-Kuvandudza Kusimba Kwetsandanyama muVakuru

Sezvo munhu akwegura, simba remhasuru, ukuru, uye kutsungirira zvinoderera zvakanyanya. Izvo zvinogona kupihwa mhosva yekudzikira kwekushanda kwemitochondria uye kuunganidzwa kwese kwekutadza mitochondria. Uku kuderedzwa kwe mitophagy kunoita basa rakakosha mukutadzisa vakwegura kuita mabasa ehupenyu hwezuva nezuva nemabasa. Mhinduro yedambudziko iri yakawanikwa seUrolithin A powder. 

Paiva nechimwe chidzidzo chakaitwa nechinangwa chekuona mhedzisiro yeUrolithin A pasimba remhasuru uye kutsungirira kune vakwegura, vanoona kuderera kwekuita mitochondrial nezera. 

Zvinoenderana nevatsvagiri vaiita ongororo yekiriniki, pakave nekugadziriswa kwekutadza mitophagy pakati pevatori vechikamu muchidzidzo ichi, zvichiratidza kujekeswa kweiyo mitochondria isingashande uye kuvandudzwa kwehutano hwemitochondrial zvachose. Kuenzaniswa neboka rakagamuchira placebo, vatori vechikamu vakapa Urolithin A kuwedzera yakashuma kuvandudzika kukuru kwekutsungirira uye simba remhasuru mumakumbo nemaoko. Ikoko kwakaderedzwa kuneta uye kuvandudzwa kwese mukukwanisa kuita mabasa ezuva nezuva. 

Vatsvagiri vakacherekedzawo kuti iyo Urolithin A yekuwedzera inogona kuve imwe nzira yekuvandudza simba remhasuru uye kusimba pakati pevakweguru vasingakwanise kuita maekisesaizi nekuda kwehutano hwemuviri kana hwepfungwa. Zvinoenderana neCentre for Disease Control and Prevention kana CDC, kurovedza muviri kwezuva nezuva kunogona kubatsira kurwisa nyaya dzekufamba, njodzi dzekudonha, uye kumwe kusagadzikana kwekufamba kune vakwegura. Nekudaro, kana izvi zvisingagoneke, kutora Urolithin A yekuwedzera inogona kuunza mitophagy kune yakajairwa mazinga, nekudaro, kuve nemhedzisiro yakafanana nekurovedza muviri. 

-Kutungamirirwa kweDuchenne Muscular Dystrophy

Zvisinei, nezvirwere zvinodzikira tsandanyama zvakadai seDuchenne Muscular Dystrophy kana DMD, mitochondrial iri mumasero haina kukwana uye mitochondria iripo haishande zvakanaka. Uyezve, muDMD, mitophagy yakaderedzwa zvakanyanya, inova nzira iyo miviri yedu inobvisa mitochondria isingashande uye inodzokorora zvirimo kuti zvisangane nepamusoro pesimba rinodiwa nemuviri. 

Imwe yetsvakiridzo yakaitwa yekudzidza mhedzisiro ye Urolithin Ihupfu pakukura kwemhasuru yakatarisana nemhedzisiro iyo yekare ine mitophagy. Vatsvagiri vakawana kuti kuwedzera neUrolithin A kwakavandudza mitophagy mazinga, vachivadzosera kune zvakajairika muscular dystrophy varwere. Migumisiro iyi yakaonekwa pamhando dzose dzemhuka uye zvidzidzo zvevanhu, zvichiratidza kuti Urolithin A inogona kushandiswa zvinobudirira kugadzirisa zviratidzo zvemuscular dystrophies. Uyezve, vatsvakurudzi vakanyora kuwedzera kwe40 muzana yehuwandu hwekupona kwemhando dzemhuka dzakapiwa Urolithin A yekuwedzera kana ichienzaniswa nevaya vasina kugamuchira chekuwedzera. Simba rekubata uye simba rekumhanya rakawedzera ne31 muzana uye 45 muzana, zvichiteerana, mumhando dzemhuka idzi. 

Imwe bhenefiti yakakosha yeUrolithin A supplementation yakacherechedzwa panguva yechidzidzo ichi yaive yekuti yakaderedza fibrosis kana mavanga emoyo uye diaphragm yemakonzo ane DMD. Uku ndiko kuomarara kwakakosha kweDMD uko kwave kugona kugadziriswa kuburikidza Urolithin Upfu.

Urolithin A (UA) Poda -03

Ndekupi Kutenga Yakanyanya Urolithin A (UA) Poda Pamhepo?

Kune akati wandei eUrolithin A vatengesi pamhepo vane avo akazvipira mawebhusaiti anogona kusarudzwa kutenga iyo metabolite. Vatengesi vezvitoro vanobvumira vashandisi kutenga Urolithin A poda pamhepo, nekutumira kuri nyore uye nenguva. Ava vatengesi vanongobata nehupfu, uye kwete zvekuwedzera zvakagadzirwa neiyi metabolite. Urolithin A supplements inogona kutengwa zvakananga kubva kumhando yawakasarudza kana kubva kuAmazon.

Usati watenga wholesale kana ma supplements, zvinokurudzirwa kuti utarise wongororo yezvigadzirwa kuti uve nechokwadi chekuti chigadzirwa chepakutanga, chine simba, uye chinoshanda chiri kutengwa. Kune akawanda dupe pamusika uye dzimwe nguva, chigadzirwa chiri kutengwa chinogona kunge chakasvibiswa nezvimwe zvinongedzo kana chepfu. Zvakanakisisa kuita kunyatsoongorora kuchengetedzwa uye kuchena kweUrolithin A powder usati warayira kunyange iyo shoma shoma.

Urolithin A yekuwedzera inowanikwa nenzira dzakasiyana senge poda kana nyoro gel capsules. Kuraira zvakananga kubva kuUrolithin. Mutengesi anogona kuita kuti zvive nyore kwauri kuti usarudze nzira yakakodzera yekuwedzera iwe pachako. Kana fomu rave ratemwa, zvakakosha kuti usarudze muyero wakakodzera iwe pachako. Zvakakosha kuchengeta mupfungwa kuti Urolithin A powder inofanira kutorwa kamwe chete pazuva, uye imwe neimwe yerosi inenge yakapoteredza 500mg. 

Pane zvakawanda zvekudya zvekudya zveUrolithin A asi hazvina kukwana kushandisa zvikafu zvakapfuma mune zvinotangira kuUrolithin A. Panofanira kuva nemhando mbiri dzebhakitiriya mumatumbo emaruva kuitira kuti ellagitannins igadzirwe kuUrolithin A. Izvi zviviri. mhando dziri, Gordonibacter pamelaeae (DSM 19378T) uye Gordonibacter urolithinfaciens (DSM 27213T).

Kana zvipenyu izvi zvisipo mumaruva emudumbu, saka munhu akabatwa haazove nekugadzirwa kweUrolithin A mumuviri. Vanhu vakadai vanofanirwa kutora ma supplements kuti agadzirise kushomeka kweUrolithin kutendeuka mumuviri.

Ndezvipi Zvatinogona Kuona Mushure meUrolithin-Upfu?

Urolithin A yakaratidza, kuburikidza nekutsvagisa kwesainzi uye zvidzidzo, kuve neanopokana-kuchembera pasimba remhasuru, saizi, uye kutsungirira. Zvikomborero zvese zvinotsigirwa nehumbowo hwesainzi uye nguva shoma iyo zvidzidzo izvi zvakaitirwa yaive mwedzi mina. Zvidzidzo izvi zvakatora mwedzi mina kana kupfuura, uye vaongorori vazhinji vakati Urolithin A yekuwedzera yaida ingangoita mwedzi mina kuburitsa mitophagy uye metabolic mabhenefiti.

Reference:

[1]Guada M, Ganugula R, Vadhanam M, Ravi Kumar MNV. Urolithin A Mitigates Cisplatin-Induced Nephrotoxicity neInhibiting Renal Inflammation uye Apoptosis mune Yekuedza Rat Model. J Pharmacol Exp Ther. 2017;363(1):58-65. doi:10.1124/jpet.117.242420.
[2] "FDA GRAS chiziviso GRN Nhamba 791: urolithin A". US Food and Drug Administration. 20 Zvita 2018. Yakadzorerwa 25 Nyamavhuvhu 2020.
[3]Landete JM (2011). "Ellagitannins, ellagic acid uye yavo yakatorwa metabolites: Wongororo nezve kwakabva, metabolism, mabasa uye hutano". Food Research International. 44 (5): 1150–1160. doi:10.1016/j.foodres.2011.04.027.
[4] Johanningsmeier SD, Harris GK (2011-02-28). "Pomegranate sechikafu chinoshanda uye nutraceutical sosi". Ongororo yegore negore yeSainzi Yekudya uye Tekinoroji. 2 (1): 181–201. doi:10.1146/annurev-food-030810-153709. PMID 22129380.
[5] Han QA, Yan C, Wang L, Li G, Xu Y, Xia X. Urolithin A attenuates ox-LDL-induced endothelial dysfunction chikamu ne modulating microRNA-27 uye ERK/PPAR-γ nzira. Mol Nutr Food Res. 2016;60(9):1933-1943. doi:10.1002/mnfr.201500827.

AASraw inyanzvi inogadzira Urolithin A (UA) poda iyo ine lab yakazvimirira uye fekitori hombe serutsigiro, zvese zvinogadzirwa zvichaitwa pasi peCGMP mutemo uye trackable quality control system. Nzira yekugadzira yakagadzikana, zvose zvekutengesa uye zvekutengesa zvinogamuchirwa.Kugamuchirwa kuti udzidze mamwe mashoko pamusoro peAASraw!

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