AASraw inogadzira NMN neNRC powders muhuwandu!

β-Nicotinamide Mononucleotide

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MUTSVENE une mukana wekupa anti-kukwegura zvigadzirwa-NMN Powder yakawanda neCGMP mutemo uye trackable mhando yekudzora system. Yedu yepakati kugadzirwa kwemwedzi inogona kusvika 1500kg. Kugamuchirwa kuti utaure nesu kuti uwane rumwe ruzivo rwekutenga:
Mamiriro: Mudura

Mapakeji Unit: 1kg / bhegi, 25kg / dhiramu

Product Description

Basic Hunhu

Product Name β-Nicotinamide Mononucleotide (NMN)
CAS Number 1094-61-7
Molecular Formula C11H15N2O8P
Formula Weight 334.22
Synonyms NMN;

β-D-NMN;

BETA-NMN;

beta-D-NMN;

NMN upfu;

NMN zwitterion;

NICOTINAMIDE RIBOTIDE;

Nicotinamide nucleotide;

Nicotimide mononucleotide.

Kuonekwa White powder
Kuchengeta uye Kubata 2-8 ° C munzvimbo yakaoma

Pfungwa Yakakosha:

AD NAD + yakakosha coenzyme inodikanwa kune hupenyu uye maseru mashandiro.

♣ Nhanho dzeNAD +, kunyanya fomu yayo yeNAD +, zvinowira pasi nezera mumatumbu mazhinji.

Body Muviri unogadzira NMN sedanho repakati kana "anotungamira" kuNAD +. Taura zvakapusa: mazinga epamusoro eNMN anoreva madanho epamusoro eNAD +.

Yakaziviswa: Pakutevera zvinyorwa, Yakashandiswa NMN pachinzvimbo che β-Nicotinamide Mononucleotide (NMN)


 

NMN Nharaunda- NAD + & NMN

NAD + chinhu chakasarudzika, chinoramba chichigadzirwa mumuviri wedu uye chinoshandiswa nema enzymes mazhinji akakosha kubatsira kusimudzira mashandiro akanaka emaseru. Zvisinei, sezvo NAD + inoshandiswa kumusoro mukugadzirisa aya masystem, isu tinotanga kupinda muNAD + kushomeka munzvimbo dzakasiyana muhupenyu hwedu, nekuwedzera kuwanda sezvatinokwegura. Sezvo aya maNAD + enzyme ane simba achiita basa rakakosha mukuchengetedza simba remagetsi, nekusimudzira hutano hwemaseru, kuderera kweNAD + kunogona kukuvadza zvakanyanya hutano hwedu.

Nekuda kweizvi, yakawanda yekutsvagisa yakatangwa mukusimudzira NAD + nhanho mumuviri. Mufungo wekusimudzira NAD + nhanho ndewekuti uchave nekutsigira kwakanyanya kweakawanda mabasa akakosha emuviri, uye nekudaro anogona kubatsira kusimudzira hupenyu hurefu. Kunyanya kukosha zvakadaro, nhanho dzakasimudzirwa dzeNAD +, hadzifanirwe kungosimudzira hurefu, zvinogona zvakare kubatsira kusimudzira hupenyu huri nani sezvo isu takura!

Saka isu tinokwidziridza sei NAD + nhanho? Izvi zvinoita sekunge zvakanyanyisa. Nekudaro, ongororo ichangoburwa yafumura chinhu chakasarudzika chinonzi Nicotinamide Mononucleotide (NMN), iyo inogona kushandiswa nemuviri seyakatangira kwazvo kuNAD +. Mune dzidziso, izvi zvinoreva kuti NMN inogona kusimudzira hupenyu hwakareba uye hune hutano!

Nekudaro, NMN haisi chete yenguva refu inonakidza inokurudzira kuwedzera. Muchokwadi, NMN inoyevedza inowedzera kune vese vadiki nevakuru vanhu, sezvo iine hunhu hunosimudzira zvisinei nezera rako. Vechidiki nevakuru vanhu vese vanoda yakakwira NAD + nhanho dzemiviri yavo nepfungwa kuti vamhanye pakakwirira kuita. Iyo yakakwira yako NAD + nhanho, inowedzera maseru esimba iwe uchave unowanikwa, uye zvirinani muviri wako nepfungwa zvichakwanisa kushanda mumamiriro anodenha zvakanyanya. Ngatitaurei kuva vakatendeseka, ndiani asingakwanise kushandisa zvishoma zvemupendero mune ino inokurumidza kufamba uye inoda nyika? Nekudaro, kana iwe uchida kubhadharisa maseru ako, uye uchida kuziva izvo muviri wako nepfungwa zvinogona kubudirira neimwe yekuwedzera NAD + kurova kutenderera, saka tinokukurudzira kuti urambe uchiverenga kuburikidza neiri rakazara blog iro rakagadzirirwa kukubatsira iwe kuwana zvakanyanya kunze kweNMN yekuwedzera!

 

Chii chinonzi NMN?

NMN (Nicotinamide Mononucleotide) ndeyemhuri yenucleotide, mamorekuru emakemikari anowanikwa mune zvakawanda zvekudya zvatinodya. Sezvo nezvose nucleotides, NMN inoumbwa nematatu zvikamu: nitrogenous base, shuga, uye phosphate boka.

Nepo akawanda ma nucleotide achishandiswa kuvaka DNA, NMN inoshandiswa kugadzira nicotinamide adenine dinucleotide (NAD +) uye nekuenzanisa simba simba. Mutumbi unogadzira NMN sedanho repakati kana "anotungamira" kuNAD +. Taura zvakapusa: mazinga epamusoro eNMN anoreva madanho epamusoro eNAD +.

NAD + inowedzera simba remutumbi remuviri (ATP), rinoyera mutinhimira we circadian, uye inogonesa mazana ema enzymatic reaction - mazhinji acho anononoka kuchembera. Nhanho dzeNAD +, kunyanya fomu yeNAD +, zvinowira pasi nezera mumatumbu mazhinji.

 

NMN Inoshanda Sei? / Nei Uchida NMN yekuwedzera?

NR neNMN zvese zvinobatsira nekuti zvinokwidziridza mazinga eNAD +, ayo anoderera nezera. NAD + yakakosha kumaseru metabolism, ichishandura zvinovaka muviri kuita simba remagetsi, uye zvakare inogonesa sirtuin, seti yemapuroteni anodzora hutano hwemagetsi. Isu tese tinowana NAD + mumiviri yedu nekuda kwekudya kwedu, nekudya chikafu neNAD + vatangiri mavari. Nepo NR neNMN ichiwanika mumatanho ezviwanikwa muzvikafu zvakasiyana siyana, zvakadaro, munhu haakwanise kudya zvakakwana zvechinhu chero chipi zvacho kusimudzira mazinga eNAD +. Nekuda kweizvozvo, kuwedzera pamwe neNAD + preursor kunogona kubatsira kudzikisira kuderera.

 

NMN inobatsira

  • NMN inowedzera magetsi mumasero ekukwegura:

Masero anotora opinza mafuta kusimbisa mashandiro avo. Sezvaunokwegura vanorasikirwa nehunyanzvi uhu, vachivamanikidza kupinda muchimiro chinozivikanwa sema cell senescence kana kuchembera kwehupenyu kunouya pamwe nezvimwe zvinokuvadza. NAD + inova chinhu chakakosha chemafuta epamasero yaifungidzirwa kuti ndiyo yega nzira inopihwa neNMN Izvi zvinoreva kuti kuwedzera neNMN kunopa yako maseru nzira inokurumidza kuita refuel uye inosimudzira kupatsanuka kwemasero uye kukura.

 

  • NMN inobatsira pakurwisa hutachiona hwehutachiona:

Sezvo iwe paunenge uchikwegura, mamiriro akadai seshuga, kufutisa, dyslipidemia, uye isiri-doro mafuta mafuta chiropa chirwere (NAFLD) inova yakawanda. Izvo zvinokonzerwa nekuderedzwa kweNAD + nhanho. NMN inoshanda kuburikidza nenzira yekununura kusimudzira iwo mazinga eNAD + nokudaro ichivandudza izvi nezvimwe zvirwere zvemagetsi.

 

  • NMN inogadziridza kudzikira kweropa kuyerera:

Sezvo muviri unokwegura, nhamba uye mashandiro emasero endothelial (ECs) anodzika tsinga dzeropa anoderera. midziyo.

 

  • NMN inodzvinyirira zera-inoenderana nehuremu kuwedzera:

Sezvo vanhu vanokwegura, vanowedzera uremu. Mune chidzidzo che2016, zvakawanikwa kuti zvidzidzo zvakapihwa NMN zvakaona mafuta avo mashoma achidzikira uye kuonda kuwanda kuwanda. Nekuwedzera neNMN, unogona kurasikirwa nehuremu uye kuvaka mhasuru-mbiri nzira dzakasimba dzekuvandudza mhasuru hutano uye kutarisa uye kunzwa kunge mudiki!

 

  • NMN inowedzera simba metabolism:

Nekudyidzana kweNAD +, NMN inobatsira kupwanya zvinovaka muviri musimba, kupa simba maseru anoshanda uye kudzora kushushikana kweiyo oxidative. Aya maitiro emakemikari anononoka uye anogona kumisa kukwegura. NMN haingosimbise simba rako chete asi inobatsira mukugadzirisa maseru ako!

 

NMN Kuchengetedza uye Matambudziko

NMN inoonekwa seyakachengeteka mumhuka, uye mhedzisiro yacho iri kuvimbisa zvakakwana kuti kuyedzwa kwevanhu kwatanga. Iyi mamorekuru inonyanya kutaridzika kuva yakachengeteka uye isina chepfu, kunyangwe pakukwirira kwakanyanya mumakonzo uye mukudzidza kwevanhu. Yakareba-gore (rimwe-gore) remuromo manejimendi mumakonzo haina huturu hunokanganisa. Yekutanga kiriniki kuyedzwa muvanhu yakapedzwa uye humbowo hunotsigira pfungwa yekuti haina chepfu mune imwe doses.

Kunyangwe kumwe kuongorora kwevarume vechiJapan kwakaburitswa munaNovember 2019 kwakaratidza kuti zvidzidzo zvakawedzera huwandu hwebilirubin muropa ravo zvichitevera hutongi hweNMN, aya mazinga akasara ari pakati peyakajairika renji. Zvidzidzo zvenguva yemberi zvinofanirwa kutarisa mukuchengetedza kwenguva refu uye kugona kwekushandisa. NMN haina kubatana nechero ipi mhedzisiro inozivikanwa.

 

NMN seNAD + Inowedzera-Yakakurumbira

Intracellular kuwanda kweNAD + kuderera kubva mukukwegura semazuva ese mashandiro emagetsi anopedza NAD + zvigadzirwa nenguva. Matanho ehutano eNAD + anofungidzirwa kudzoreredzwa nekuwedzera pamwe neNAD + vatangiri. Zvinoenderana nekutsvagurudza, ivo vekutanga vakaita seNMN uye nicotinamide riboside (NR) vanoonekwa sevanowedzeredza ekugadzira kweNAD +, kuwedzera kuwanda kweNAD +. David Sinclair, muongorori weNAD + anobva kuHarvard, anoti, "Kudyisa kana kupa NAD + zvakananga kuzvinhu hazvisi nzira inoshanda. Iyo NAD + mamorekuru haigone kuyambuka nyore nyore masero echipinda kuti apinde mumasero, uye nekudaro inenge isingawanikwe kuti igadzirise metabolism. Panzvimbo iyoyo, mamorekuru ekutanga kuNAD + anofanirwa kushandiswa kuwedzera mwero weNNAD + usingawanikwe. ” Izvi zvinoreva kuti NAD + haigone kushandiswa seyakananga yekuwedzera, nekuti haisi nyore kupinza. NAD + vatangiri vanobatwa zviri nyore kupfuura NAD + uye zvinoshanda zvakanyanya zvinowedzera.

 

Unofanirwa Kuziva Usati Watenga NMN Powder Pamhepo

 

Chimiro chisina kugadzikana.

Chizvarwa chekutanga cheNMN nehuremu hwakaderera hwakanga husina hunyoro hwakanyanya. Shanduro yakagadziridzwa yeAASraw yeNMN inounza pasi mutengo wekugadzira kuburikidza nani upfu kuyerera kunotungamira mukuwedzera kugona kwekugadzira sezvo zvichange zviri nyore kumhanya nemumachina. Zvakare, iyi vhezheni inotungamira kune imwe yunifomu muyero wemacapsule sezvo iyo yakaderera density vhezheni iri kunetsa kusanganisa zvakafanana. Chekupedzisira, yakaderera density NMN upfu hwakatsindirwa mufiritsi fomu inogona kupararira nyore panguva yekufamba.

Vatengi vazhinji vanoedza kugadzirisa izvi nekuwedzera zvinowedzera asi izvo zvinotungamira kune makuru mahwendefa, ayo asiri akakodzera kune vatengi mune yakura tarisiro yevanhu. Nekudaro, yakaderera density NMN inongokodzera chete hupfu chigadzirwa zvigadzirwa.

 

▲ Inundated Yakashatiswa NMN zvigadzirwa.

Iwo musika zvinosuruvarisa mafashama neNMN yekunyepedzera uye yakashatiswa. Kubva zvakapinda NMN mumusika gore rapfuura akawanda matsva eNMN mabhendi akaonekwa imwe mushure meimwe. Zvakaoma kwazvo kune vagadziri uye vatengi vedu kuti vataure izvo chaizvo zvemhando yepamusoro zvinhu kubva kune zvisiri izvo uye zvakaderera-kuchena zvigadzirwa zvinotengeswa online.

Zvimwe zvigadzirwa zveNMN zvinotengeswa zvine pasi pe80% kuchena. Vatengi uye vatengi havangomboziva kuti ndezvipi zvinozadza kana zvinosvibisa zvirimo mune imwe 20% yechigadzirwa.

Isu takanyatsoona kuti vazhinji veNMN vatengesi vanogona kutengesa nicotinamide (yakajairika yakachipa vhitamini B3) kana nicotinamide riboside panzvimbo yeNMN. Kunyangwe vamwe vatengesi vanowedzera hupfu kuti isanganise iyo NMN uye vanyengere vatengi vavo. Izvi zvigadzirwa zvinowanzo kuve zvakachipa asi zvakare pasina chero zvinobatsira.

 

Kushaikwa kwekuchengetedza uye data rinoshanda.

NMN inowedzera kuwedzera kufarirwa muUS, Europe, Japan neChina, nezvimwewo, asi yakawanda yekuchengetedza uye data rinoshanda richiri kushomeka. Vanhu vazhinji vachiri kusavimba nechigadzirwa ichi, saka musika weNMN unogaro ganhurirwa. Chaizvoizvo NMN yakatanga kuvapo mumuviri wemunhu uye mimwe miriwo yakaita sebroccoli, saka haina chekuchengetedza. Asi inguva yakakwira yedata ichienderera ichiongorora kushanda kwayo.

 

[Reference]

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[6] Mills KF, Yoshida S, Stein LR, Grozio A, Kubota S, Sasaki Y, Redpath P, Migaud ME, Apte RS, Uchida K, Yoshino J, Imai SI. Yenguva Yakareba Kutungamira kweNicotinamide Mononucleotide Inogonesa Zera-Yakabatana Physiological Kupera muMakonzo. Cell Metab, 2016; DOI: 10.1016 / j.cmet.2016.09.013.

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