Tenga Trilostane Powder (13647-35-3) hplc≥98% | AASraw
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Trilostane Upfu (13647-35-3)

Rating: SKU: 13647-35-3. Category:

MUTSVENE unobatanidzwa uye unogadzira kugona kubva ku gram kusvika pakuteerana kweTrilostane Powder (13647-35-3), pasi peCGMP mutemo uye neinoteedzera mhando yekudzora mhando.

Product Description

 

Trilostane Powder (13647-35-3) vhidhiyo

 

 


 

Trilostane Upfu (13647-35-3) S.pecification:

Chemical Kuumbwa: Product Name: Trilostane
Cas.: 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.43
Standard: In-house
Kuchengetedza: Kuoma, kusviba uye pa0 - 4 C kwenguva pfupi (mazuva kusvika kumavhiki) kana -20 C kwenguva refu (mwedzi kusvika makore).
Zvinyorwa (COA & HPLC nezvimwewo): Available

 

Trilostane Upfu (13647-35-3) D.nhoroondo:

Trilostane powder is inhibitor ye3β-hydroxysteroid dehydrogenase inoshandiswa pakurapa kweCushing's syndrome uye yekutanga hyperaldosteronism. Izvi zvese zviri zviviri kusagadzikana uko kwakanyanyisa huwandu hwecorticosteroid mahormoni anogadzirwa mumuviri. Corticosteroids yakakosha kuti muviri ushandise makabhohaidhiretsi, mafuta uye mapuroteni uye nemhinduro yakajairika kunetseka. Izvo zvakare zvakakosha pakurongedzwa kwemunyu uye chiyero chemvura mumuviri. Trilostane poda inobatsira kudzivirira kugadzirwa kwecorticosteroids, kudzora zviratidzo zvine chekuita nezvinetso izvi.

Trilostane poda inogona zvakare kubatsira pakurapwa kwegomarara repazamu radzokerazve mune vakadzi vakapfuura nekuenda kumwedzi.

Ive ichangobvumidzwa muna2008 yekurapa chirwere cheCushing (hyperandrenocorticism) muimbwa. Ndiwo zvakare mushonga wekutanga unobvumidzwa kurapa ese pituitary- uye adrenal-anoenderana neCushing imbwa. Iyi mishonga yemishonga inoshanda nekumisa kugadzirwa kwecortisol mune adrenal glands.

 

Dheuteronomio:

  •  1: Midence JN, Drobatz KJ, Hess RS. Cortisol Concentrations mune Idzo dzakarongeka Imbwa neHyperadrenocorticism Yakaitirwa naTrilostane. J Vet Intern Med. 2015 Nov; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. PubMed PMID: 26374943.
  • 2: Fracassi F, Corradini S, Floriano D, Boari A, Aste G, Pietra M, Bergamini PF, Dondi F. Practostic zvinhu zvekupona imbwa dzine pituitary-based hypercortisolism yakarapwa ne trilostane. Vet Rec. 2015 Jan 10; 176 (2): 49. doi: 10.1136 / vr.102546. Epub 2014 Aug 28. PubMed PMID: 25170036.
  • 3: Bonadio CM, Feldman EC, Cohen TA, Kass PH. Kufananidza kwe adrenocorticotropic hormone kukurudzira miedzo yakatanga 2 pamwe neawa mana mushure mekutora kwetrostostane imbwa dzinowanzoitika hyperadrenocorticism. J Vet Intern Med. 4 Jul-Aug; 2014 (28): 4-1239. doi: 43 / jvim.10.1111. Epub 12357 Chivabvu 2014. PubMed PMID: 26.