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Cortexolone 17α-propionate powder

Rating: SKU: 19608-29-8. Category:

MUTSVENE unobatanidzwa uye unogadzira zvigadzirwa kubva kugiramu kusvika pakukura kwe Cortexolone 17A-propionate powder (19608-29-8), pasi peCGMP mutemo uye trackable quality control system.

Product Description

 

Cortexolone 17α-propionate powder video

 

 


 

Cortexolone 17α-propionate powder Basic Characters

 

Name: Cortexolone 17α-propionate powder
CAS: 19608-29-8
Molecular Formula: C24H34O5
Molecular Kurema: 402.52
Melt Point:
Storage Temp: Room Temperature Temperature
Color: Muchena kusvika pachena-pfu pfupa yeupfu

 


 

Cortexolone 17α-propionate cycle

 

Mazita

CAS: 19608-29-8
Kemikari Mazita: cortexolone-17α-propionate,
Mamwe Mazita: CB-03-01, Winlevi powder, Breezula powder, 11-deoxycortisol 17α-propionate, Cortexolone 17α-propionate powder

 

Cortexolone 17α-propionate Usage

Cortexolone 17A-propionate inoshandiswa steroidal antiandrogen - kunyanya, anrogen anorgen receptor - iyo iri pasi pekusimbiswa neCassiopea uye Intrepid Therapeutics kuti ishandiswe semishonga yepichepi mukurapa mamiriro ezvinhu anonzi androgen-kusanganisira acne vulgaris uye androgenic alopecia (murume-pattern kuputsika kwemvere).

 

Ndeipi iyo inonzi Cortexolone 17α-propionate

Cortexolone 17A-propionate 1% kamu, mushonga mutsva unorwisa antirogenrogen yepamusoro-soro wehutachi vulgaris. Mutevedzeri wechikwata anonzi randomized, double-blind comparing study vs. placebo uye tretinoin 0 · 05% kamu.

MARARAMIRO

Acne vulgaris chirwere chechikwata chechipiri chinogadziriswa umo inonzi androgens inobatsira kutanga kwayo nekushingaira. Kushandiswa kwe antiandrogen naizvozvo kunogona kushanda; zvisinei, antiandrogens yekushandiswa kwemashoko emitambo haisipo pamusika. Cortexolone 17A-propionate ichinhu chitsva chinonzi antiandrogen chinogona kushandiswa muzvinyorwa zvinopisa.

ZVINANGWA

Kuongorora kuchengetedza uye hutano hwehutano hweCortexolone 17A-propionate 1% kamu muAcne vulgaris kana uchienzaniswa ne placebo uye neTretinoin 0 · 05% kamu.

METHODS

Makumi manomwe nemanomwe evarume vane huso kumeso vakarova 2-3 zvinoenderana neInvestigator's Global Assessment (IGA) vakasarudzika kugamuchira placebo cream (n = 15), kana Cortexolone 17α-propionate 1% cream (n = 30), kana tretinoin 0 · 05 % kirimu (n = 32) kamwe pazuva pazuva panguva yekurara kwemasvondo masere. Clinical efficacy yakaongororwa mavhiki maviri ese kusanganisira yakazara lesion count (TLC), inflammatory lesion count (ILC), acne severity index (ASI) uye IGA. Kuchengetedza kwekuchengetedza kwakasanganisira mamaki ekutsamwa enzvimbo, bvunzo dzevarabhoritari, kuongorora kwemuviri, zviratidzo zvakakosha uye kurekodha kwezviitiko zvakashata.

RESULTS

CB-03-01-cream yakagadziriswa zvakanaka, uye yaive yakakosha kupfuura placebo pamusoro peTLC (P = 0 · 0017), ILC (P = 0 · 0134) uye ASI (P = 0 · 0090), uyewo kuchipatara zvinobudirira zvikuru kupfuura kufananidza. Chigadzirwa chacho chakakonzera kukurumidza kukurumidza kwe50% kuvandudzwa mune zvose zvataurwa pamusoro apa. CB-03-01

CONCLUSIONS

Ichi chidzidzo chekutsvaga chinotsigira chikonzero chekushandiswa kwemashoko anonzi antiandrogens mukurapa acne vulgaris. Cortexolone 17A-propionate 1% kamu cream inofananidzwa yakakodzana nehuwandu hwean antiandrogen yakanaka yekushandiswa kwemashoko.

 

Iyo Cortexolone 17A-propionate inoshanda sei

Cortexolone 17A-propionate (CAS 19608-29-8), kana 11-deoxycortisol 17α-propionate, inoshandiswa steroidal antiandrogen - kunyanya, anopesana neaorrogen receptor - iyo iri pasi pekusimbiswa neCassiopea uye Intrepid Therapeutics kuti ishandiswe semishonga yepicopic in kurapwa kwemamiriro ezvinhu a androgen-anogadzikana kusanganisira acne vulgaris uye androgenic alopecia (kurasikirwa nevhudzi-bvudzi). Ndiyo C17α propionate ester ya 11-deoxycortisol (cortexolone); C17A esters ye11-deoxycortisol yakanga isingatarisirwi kuti ine nhaka ye antiandrogen, uye cortexolone 17α-propionate yakasarudzwa kuti ibudirire zvichienderana nehuwandu hwehuwandu hwezvinodhaka.

Mumakonzo, mishonga iyi yakawanikwa iine simba yakasimba yepano antiandrogen, asi isingabatsiri systemic antiandrogen iyo inotungamirirwa kuburikidza nehutachiwana hutachiona. Mukuwedzera, cortexolone 17A-propionate haisi progonadotropic, inoratidza kuti iri kusarudzwa kamwechete. Mune chimiro chemhuka, chironga chemusoro chechirwere chakanga chiri chikuru kune cheprogesterone, flutamide, uye mari yemari uye yakanga yakaenzana neyeyproterone acetate.

Mutyairi wechipatara mutsva mu 2011 yevarume vaibatwa netikitikiti cortexolone 17α-propionate 1% kamu yeakoni yakawana kuti mishonga yakanyatsorambidzwa uye yakaderedza zvikuru zviratidzo zvepine. Uyezve, kubudirira kwacho kwaive kwakakura kudarika kweyomuenzanisi anoshanda, tretinoin 0.05% cream. SezvaA2017, mushonga uyu uri muchitsauko III kliniki miedzo ye acne vulgaris uye chirongwa chechipiri chemakiriniki ye androgenic alopecia.

 

yambiro

Cortexolone 17α-proprionate, Breezula powder mumhando dzayo dzepolymorphic: mhuri yekutanga patent, inopera muUnited States muna 2022/23 uye muna 2022 kune dzimwe nyika, inobata kushandiswa kwechiremba kwekomboni yekurapa acne, alopecia uye zvimwe zvirwere; yechipiri patents mhuri inovhara ese anozivikanwa macristalline mafomu eAPI, nziyo dzine iyo imwechete API uye zvine chekuita nekurapa kushandiswa pakurapa acne, AGA uye zvimwe zvirwere: iyi mhuri yepamutemo yakatopihwa muUnited States, Europe, Canada, Japan uye dzimwe nyika, dzichapera muna 2030 muUnited States uye 2028 mune dzimwe nyika.Breezula powder

 

Cortexolone 17α-propionate Raw Powder

Min order 10grams.
Inobvunza pamusoro pezvakawanda (mukati 1kg) inogona kutumirwa mumaawa e12 mushure mekubhadhara.
Kuti uwedzere kurongeka kunogona kutumirwa mumazuva ekushanda kwe3 mushure mekubhadhara.

 

Cortexolone 17A-propionate Raw Powder Recipes

Kubvunzurudza Mutengi wedu Mumiririri (CSR) nezvemashoko, nekuda kwekutaura kwako.Winlevi powder

 

Cortexolone 17α-propionate Marketing

Kuti igoverwe mune ramangwana riri mberi.

 

Ko Cortexolone 17A-propionate Iine Mhinduro Dzakashata

Cortexolone 17A-propionate inoshandiswa steroidal-ester, inoparadzanisa uyerogen-antagonist, inopiwa basa risiri rinopisa simba, iro rinoratidzika rakakodzera zvakakodzera kurapa acne vulgaris. CB-03-01 inoshanda pamunhu we-androgen-receptor pasina kuvhara 5α-kuderedza mucheche. Steroid iri nyore kupinda mukati meganda revanhu uye inokurumidza kugadziriswa kuti isunungure mubereki cortexolone iyo isingashandisi systemic effects. Zvinonyanya kukosha, kuti uwane ushamwari, hazvina kuratidza chero mamiriro ezvinhu emunharaunda kana sitiroid madhara.

 


 

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1.Kutaurirana nesu ne email yedu yekubvunza system, kana online skypeMutariri wevashandi (CSR).
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