γ-Aminobutyric acid (GABA) poda - Mugadziri Fekitori Mutengesi
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γ-Aminobutyric asidhi (GABA)

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GABA inotorwa nemuromo kudzikisira kushushikana, kugadzirisa manzwiro, kudzikisa zviratidzo zve premenstrual syndrome (PMS), nekurapa kushomeka-kusagadzikana kwehutano (ADHD). Iyo inoshandiswawo kusimudzira kuonda kwemhasuru kukura, kupisa mafuta, kudzikamisa BP, uye kubvisa marwadzo.

Product Description

Basic Hunhu

Product Name γ-Aminobutyric asidhi (GABA)
CAS Number 56-12-2
Molecular Formula C4H9NO2
Formula Weight 103.12
Synonyms 4-aminobutyric acid

4-Aminobutanoic asidhi

gamma-aminobutyric acid

GABA

56-12-2

Kuonekwa White powder
Kuchengeta uye Kubata Kuoma, kusviba uye 0 - 4 C kwenguva pfupi, kana -20 C kwenguva refu.

 

γ-Aminobutyric asidhi (GABA)tsananguro

γ-aminobutyric acid, kana gamma-Aminobutyric acid, kana GABA, ndiyo inodzivirira neurotransmitter mune inosimudzira mammalian central nervous system. Basa rayo rakakosha kudzora kushushikana kwenzvimbo mukati mehurongwa hwetsinga.

GABA inotengeswa sekuwedzera kwekudya munyika zhinji. Izvo zvave zvakagara zvichingofungidzirwa kuti exogenous GABA (kureva kutorwa sekuwedzera) haiyambuke ropa-huropi chipingamupinyi, zvisinei data rakawanikwa kubva kutsvagurudzo yazvino inoratidza kuti zvinogona kudaro.

 

γ-Aminobutyric acid (GABA) Mashandiro Ekuita

Zvinodhaka zvinoshanda senge allosteric modulators eGABA receptors (inozivikanwa seGABA analogues kana GABAergic madhiragi), kana kuwedzera huwandu hunowanikwa hweGABA, hunowanzo kuve nekuzorora, kupokana-kuzvidya mwoyo, uye zvinopesana nemhedzisiro. Zvizhinji zvezvinhu zviri pazasi zvinozivikanwa nekukonzera anterograde amnesia uye kudzoreredza amnesia.

Kazhinji, GABA haina kuyambuka ropa-huropi chipingamupinyi, kunyangwe dzimwe nzvimbo dzehuropi dzisina ropa rinoshanda-huropi, senge periventricular nucleus, inogona kusvikwa nemishonga yakadai sehurongwa hwakajowa GABA. Chidzidzo chimwe chete chinoratidza kuti GABA yemumuromo inowedzera huwandu hwevanhu kukura mahormone (HGH). GABA yakakwenenzverwa zvakananga kuuropi yakanzi ine zvese zvinokonzeresa uye zvinokanganisa kugadzirwa kwekukura kwehomoni, zvinoenderana nehunhu hwemunhu. Zvimwe pro-zvinodhaka zveGABA (ex. Picamilon) zvakagadzirwa kuti zvipinde muropa-huropi chipingamupinyi, zvobva zvaparadzaniswa muGABA uye inotakura mamorekuru kamwe mukati meuropi.

GABA yakawedzera iyo catabolism yeserotonin muN-acetylserotonin (iyo inotungamira melatonin) mumakonzo. Saka zvinofungidzirwa kuti GABA inobatanidzwa mukuumbwa kwemelatonin uye nokudaro inogona kuita zvinodzora pakurara nemabasa ekubereka.

 

γ-Aminobutyric asidhi (GABA) kunyoresa

Gamma-Aminobutyric Acid inowanzoitika neurotransmitter ine central nervous system (CNS) inhibitory chiitiko. Gamma-aminobutyric acid (GABA), inoshandurwa kubva kune huru inofadza neurotransmitter glutamate muuropi, inoita basa mukugadzirisa kushushikana kweiyo neuronal nekusunga kune ayo anogamuchira, GABA-A uye GABA-B, uye zvichidaro zvichikonzera ion chiteshi kuvhura, hyperpolarization uye pakupedzisira kudzivirirwa kweurotransmission.

Gamma-aminobutyric acid iri gamma-amino acid iyo iri butanoic acid ine chinotsiva amino chiri paC-4. Ine basa sekuratidzira mamorekuru, munhu metabolism, Saccharomyces cerevisiae metabolite uye neurotransmitter. Iyo iri gamma-amino acid uye monocarboxylic acid. Inobva kune butyric acid. Iyo conjugate acid yegamma-aminobutyrate. Iyo tautomer yegamma-aminobutyric acid zwitterion.

 

Zvakanakira γ-Aminobutyric acid (GABA)

GABA inotorwa nemuromo kudzikisira kushushikana, kugadzirisa manzwiro, kudzikisa zviratidzo zve premenstrual syndrome (PMS), nekurapa kushomeka-kusagadzikana kwehutano (ADHD). Iyo inoshandiswawo kusimudzira kuonda kwemhasuru kukura, kupisa mafuta, kudzikamisa BP, uye kubvisa marwadzo.

 

Reference

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6, Sato S, Yinc C, Teramoto A, Sakuma Y, Kato M (2008). "Zvepabonde dimorphic modulation yeGABA (A) yekugashira mafashama nemelatonin mumakonzo gonadotropin-kusunungura mahormoni neurons". J Physiol Sci. 58 (5): 317–322. doi: 10.2170 / physiolsci.rp006208. PMID 18834560.

7, Kuriyama K, Sze PY (Ndira 1971). "Ropa-huropi chipingamupinyi kuH3-γ-aminobutyric acid mune yakajairwa uye amino oxyacetic acid-inorapwa mhuka". Neuropharmacology. 10 (1): 103-108. doi: 10.1016 / 0028-3908 (71) 90013-X. PMID 5569303.

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