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Apixaban powder

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SKU: 503612-47-3. Category:

MUTSVENE unobatanidzwa uye unokwanisa kugadzira kubva ku gramu kusvika mukuraira kweApixaban powder (503612-47-3), pasi peCGMP mutemo uye trackable quality control system.

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Product Description

Apixaban powder video


Apixaban powder Basic Characters

Name: Apixaban powder
CAS: 503612-47-3
Molecular Formula: C25H25N5O4
Molecular Weight: 459.50
Melt Point: 238-240 ° C
Storage Temp: 20 ° C kusvika 25 ° C
Color: Muchena kuchena-yellow poda


Apixaban powder mbiriso yakasviba

Mazita

Apixaban powder

Apixaban powder Uswa hwekushandisa hwepfuu

Dosage Modifications
Kutungamirirwa nemhando mbiri inhibitor yeYPPNUMXA3 uye P-gp

Kana kutora> 2.5 PO BID, kuderedza dose ne50%
Kana uchitora 2.5 mg BID, usapinda mutungamiri nemasimba maviri maviri
Nonvalvular atrial fibrillation

Deredza chiremba ku2.5 mg PO BID kune varwere vane chero 2 yezvinhu zvinotevera:
Zera ≥80 makore
Weight ≤60 kg
Serum creatinine ≥1.5 mg / dL

  • Kugadziriswa Nengozi Yokurohwa / Kurongwa Kwekugadzikana muNyvalvular Atrial Fibrillation, 5 mg (Vanhu Vakuru) kaviri zuva nezuva; Chero 2 yeiyi: makore ≥80 yr, uremu ≤60 kg, serum creatinine ≥1.5 mg / dL- 2.5 mg kaviri zuva nezuva; Kushandiswa kwemhepo yakasimba ye-strong inhibitors yeYPPYNUMXA3 uye P-gp- 4 mg kaviri zuva rimwe nerimwe; kana murwere achitotora 2.5 mg kaviri zuva rega rega, rega kushandiswa kushandiswa.
  • Renal Impairment, HD- 5 mg (Vanhu vakuru) kaviri zuva nezuva; HD uye imwe nguva ≥80 yr kana uremu ≤60 kg- 2.5 mg kaviri zuva nezuva.
  • Kudzivirirwa Kwemvura Yakadzika Kufuridzira Kutevera kana Hip Replacement Surgery, 2.5 mg (Vanhu vakuru) kaviri zuva rimwe nerimwe, yakatangwa 12-24 hr post-operatively (apo hemostasis inogadziriswa) yakaenderera mberi kwemazuva 35 mushure mekunyanya kuchinjwa kana kuti 12 mazuva mushure megadziriro.
  • Kurapa kweDVT kana PE, 10 mg (Vakuru) kaviri zuva rimwe nerimwe kwemazuva 7, uye 5 mg kaviri zuva nezuva.
  • Kuderedza kuipa kwekudzoka kweDVT kana PE, 2.5 mg (Vanhu vakuru) kaviri zuva rimwe nerimwe mushure me ≥6 mo yekurapa kweDVT kana PE.

Warning on Apixaban powder powder raw

Izvo zvinowanzoburwa nemigumisiro yechirwere iri kubuda ropa uye kupera kwemawere, taurira chiremba wako kana kuwana rubatsiro rwechirwere pakarepo kana uine chimwe chezviratidzo kana zviratidzo zvinotevera zvingave zvakabatana nehuipi hwakaipa.

  • Zviratidzo zvehutano hwehutachiona, sekushanduka; mikoko; itching; tsvuku, kupfigira, kubvongodzwa, kana kupfekedza ganda kana kuti isina fevri; wheezing; kuoma mubhokisi kana muhuro; kunetseka kufema, kumedza, kana kutaura; hoaseness isina kujairika; kana kuzvimba kwemuromo, chiso, miromo, rurimi, kana huro.
  • Zviratidzo zvekubuda ropa sekukandira ropa kana kukanda kumusoro kunoita segomba rekofi; achikandira ropa; ropa mumuguta; dema, tsvuku, kana tarry zvigaro; kubuda kubva kumadzimai; chirwere chepamuviri chechikadzi chisina kuchena; marwadzo pasina chikonzero kana icho chinokura; kana kubuda chero kupi zvako kwakaipa kana kuti iwe haugoni kumira.
  • Kutsiva kana kubuda kunze.
  • Kushungurudza pamwe chete kana kuzvimba.
  • Kuchepa kwepfupa kana kuomeswa.
  • Kunzwa kuneta kana kushaya simba.
  • Kunzwa kuvhiringidzika.
  • Headache.
  • Wheezing.

Bleeding
Apixaban powder inogona kuwedzera njodzi yekubuda ropa iyo inogona kuva yakaoma uye inogona kuuraya. Kushandisa pamwe chete nemishonga inobatsira hemostasis inogona kuwedzera kuwedzera iyi ngozi. Izvi zvinosanganisira zvinodhaka zvakadai semamwe anticoagulants, heparin, aspirin, antiplatelet zvinodhaka, sarotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, uye nhengo dzisiri dzechirwere zvinopikisa (NSAIDs).

Imwe inonetseka nekushandiswa kweApixaban powder uye imwe iyo itsva anticoagulants ndekushayikwa kwetsika yakagadziriswa yekushandurwa kwebasa ravo (hapana antidote iripo). Ichi chinhu chinonyanya kukosha chinosanganisira warfarin apo kubuda ropa kunowanika, kana apo vanhu vanotora mishonga vanoda chirwere chekukurumidzira.

Chirwere chemukati
Apo chirwere chepelinha / epidural anesthesia kana kupora chinoshandiswa, varwere vari kurapwa nevanorwisa-thrombotic agents kuti kudzivirirwa kwezvinetso zve-thromboembolic vari pangozi yekuvandudza hematoma, iyo inogona kukonzera nguva refu kana kuparara kwechirema. Ngozi yeiyi inogona kuwedzerwa nekushandiswa kwepadural or intrathecal catheters mushure mekuvhiyiwa kana kubva kumashandisirwo emakiriniki anoshandiswa panguva iyo inobatsira hemostasis.

Mamwe mirayiridzo

Apixaban powder inoratidzira anticoagulant uye yakananga inhibitor ye Factor Xa iyo inoshandiswa kuderedza dambudziko rehutachiona hwehutachiona, hutachiona hwehutachiona uye hurova muvarwere vane hutachiona hwetrial, uye kuderedza ngozi yechipfuva chetapisiki uye chemapurus embolus mushure megumbo . Apixaban powder yakabatanidzwa nehuwandu hwezinga re serum aminotransferase elevations panguva yekurapa uye kune dzimwe nguva dzisina kuonekwa dzechipatara zvinokuvadzwa nechiropa.

Mishonga inoshandiswa:
Apixaban powder inoratidzwa pane zvinotevera:

Kuderedza njodzi yekurohwa uye kubolism kune varwere vane nhengo dzisina kufanirwa neutrial fibrillation.
Deep vein thrombosis (DVT) prophylaxis. DVTs inogona kutungamira ku pulmonary embolism (PE) mumabvi kana kuputira kuvhiya varwere.
Kurapa kwezvose DVT ne PE.
Kuti kuderedze njodzi yekudzokorora DVT uye PE mushure mekurapa kwekutanga.

Apixaban Raw Powder

Apixaban powder yakachena kuchena-yellow powder. Patsigiro yepH (1.2-6.8), Apixaban powder haiti ionize; iyo aqueous solubility kudarika muviri wepH range ndeye ~ 0.04 mg / mL.

Mahwendefa eEliquis anowanikwa munyaya dzekunyora mumagetsi e2.5 mg uye 5 mg yeApixaban powder pamwe nemashizha asingashandisi maitiro: anhydrous lactose, microcrystalline cellulose, croscarmellose sodium, sodium lauryl sulfate, uye magnesium stearate. Iyo yokuputira mafirimu ine lactose monohydrate, hypromellose, titanium dioxide, triacetin, uye yellow iron oxide (mapiritsi e2.5 mg) kana tsvuku yesimbi (5 mg mapiritsi).

Min order 10grams.
Inobvunza pamusoro pezvakawanda (mukati 1kg) inogona kutumirwa mumaawa e12 mushure mekubhadhara.
Kuti uve mukuru (mukati 1kg) inogona kutumirwa muC3 kushanda kwemashure mushure mekubhadhara.

Apixaban powder Marketing

Kuti igoverwe mune ramangwana riri mberi.


Nzira yekutenga Apixaban powder kubva kuAASRAW

1.Kutaurirana nesu ne email yedupasina mvumo yekubvunzurudza, kana kuti inotenga skypepasinaMutariri wevashandi (CSR).
2.Kutipa isu yakabvunzwa nekero.
3.Our CSR ichakupa iyo quotation, nguva yekubhadhara, nhamba yekutsvaga, nzira yekuendesa uye inofungidzirwa zuva rekuuya (ETA).
4.Payment yakaitwa uye zvigadzirwa zvichaendeswa mumaawa e12 (Kurongeka mukati me10kg).
5.Goods inogamuchira uye inopa mhinduro.

KUGADZIRIRA UYE KUDZIDZA:

Ichi Chinyorwa Kutengeswa Kwekutsvagisa Chete Chete. Mitemo Yekutengesa Nyorera. Kwete Yekushandiswa Kwevanhu, kana Kurapa, Veterinary, kana Kushandisa Kweimba.


COA

HNMR

Apixaban powder (503612-47-3) hplc =98% | AASraw HNML

Recipes

Apixaban Raw Powder Recipes:

Kubvunzurudza Mutengi wedu Mumiririri (CSR) nezvemashoko, nekuda kwako.

References & chigadzirwa mhizha

Apixaban (Eliquis): anoshandisa, kubatana, migumisiro, kunyeverwa