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J 147 powder

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5.00 kupererwa ne 5 maererano ne 1 kasitoma Rating
SKU: 1146963-51-0. Category:

MUTSVENE unobatanidzwa uye unokwanisa kugadzira kubva ku gram kusvika kuhutachire hweJ 147 powder (1146963-51-0), pasi peCGMP mutemo uye trackable quality control system.

J147 powder yakatanga kugadzirwa mu2011, uye vatsvakurudzi vakaita zvidzidzo zvakawanda zvinoratidza kuti zvinogona kuchinja kukanganwa kwekurangarira uye kunonoka kana kushandura kuAlzheimer mumakonzo. Asi kusvikira ichi chidzidzo, vakanga vasingazivi kuti zvakashanda sei mumasero. Vakakwanisa kuratidza kuti pfupa reJ147 rinoshanda nekushandisa ATP, puroteni mu mitochondria uye nemuviri wesimba rine simba. Apo J147 powder yakanga iripo, neuroni dzakadzivirirwa kubva kune zvinokonzerwa neutano. Zvimwe zviongorori zvakaratidza kuti J147 powder inowedzera mazinga eAAT uye inosimudzira mitechondria yakagwinya, yakasimba

Product Description

J 147 powder video


Raw J 147 powder basic Characters

Name: J 147 powder
CAS: 1146963-51-0
Molecular Formula: C18H17F3N2O2
Molecular Weight: 350.3349896
Melt Point: 177-178 ° C
Storage Temp: 4 ° C
Color: Muchena kana kuti upi pfupa chena


Raw J 147 powder mukuwedzera huropi hunoita uye humwe huwandu hwekuwedzera

Mazita

J 147 powder

J 147 (1146963-51-0) Mishonga yekushandisa

Kushandisa chirongwa chekutsvaga zvinodhaka cheAlzheimer's disease (AD) iyo yakavakirwa pamatambudziko akawanda ekukwegura, takaratidza mutsara wakasimba nehutano mu rodent memory uye AD mhando dzemhando. Sezvo ichi chidimbu, J-147 powder, inonzi phenyl hydrazide, pakanga pane kunetseka kuti inogona kugadzirwa nemafuta kunonhuhwirira amines / hydrazines iyo inogona kunge inokonzera kemikari. Kuti tiongorore ikozvino, takaongorora metabolites yeJ 147 powder muvanhu uye microsomes mouse uye mouse plasma. Inoratidzirwa kuti J-147 (1146963-51-0) poda haikwanisi kugadzirwa nemafuta kunonhuhwirira amines kana hydrazines, kuti scaffold inonyanya kugadzikana, uye kuti metabolite inokonzera hutachiona hainawo neuroprotective. Zvinogumiswa kuti ma metabolite makuru eJ 147 (1146963-51-0) poda anogona kubatsira muitiro wehupenyu mumhuka.
J 147, yakabva ku curry spice component curcumin, ine uwandu hwehutano uye chaizvoizvo inodzokorora kukanganisa mumaketani anowanikwa neAlzheimer's.

J 147 (1146963-51-0) yaiva protochondrial protein inozivikanwa seAtP synthase, kunyanya ATP5A, chikamu cheprotini iyoyo. ATP synthase inobatanidzwa muchizvarwa chemitochondrial cheAAT, iyo masero anoshandisa simba.

Vatsvakurudzi vakaratidza kuti nekuderedza basa reAtp synthase, vakakwanisa kuchengetedza masero e-neuronal kubva kune zvakashata zvinokonzerwa nekukwegura kweuropi. Chimwe chikonzero cheiuroprotective effect iyi inofungidzirwa kuti iyo inobatsira yeexitotoxicity mu neuronal cell kusakara.

Excitotoxicity ndiyo chirwere chinokonzerwa neuroni uye chakaurayiwa nekugadziriswa kwemakagadziri emucherechedzo wekunakidza neurotransmitter glutamate. Funga nezvazvo sechinhu chakaita sechitsinho chechiedza chiri kushandurwa uye chichibhururuka zvakakurumidza zvokuti chinopedzisira chichiita kuti bhozo rekuvhenekera rive.

Munguva pfupi yapfuura, basa reAtP synthase inhibition nokuda kwemauroprotection contre marital excitotoxic rakaratidzwa mukudzidza kweguru [4]. Chidzidzo chechipiri chakaratidza kuti maonde akaratidza maitiro evanhu eAtantase mutant inhibitory factor 1 (hIF1), iyo inokonzera kusachengetedzwa kwakasimba kweAtP synthase, yakanyanya kugadzikana neuronal kufa mushure mekuvhiringidzwa kweexitotoxic. Iyi dheta inopindirana neyiyi itsva yeJ 147 yekudzidza, umo kuwedzera kwe IF1 mumakonzo kwakaderedza basa reAtP synthase (kunyanya ATP5A) uye raive neuroprotective.

Warning on Raw J 147 powder

Dhiyabhorosi inoratidzwa pano inoratidza kuti J-147 powder inokwanisa kukonzera kukanganisa kwepfungwa apo inoshandiswa pakupedzisira kwechirwere ichi. Kukwanisa kweJ-147 powder kunatsiridza chiyeuchidzo kune vakwegura AD mice inobatanidzwa neyo induction ye neurotrophic zvinhu NGF (nerve growth factor) uye BDNF (ubongo hunogadziriswa neurotrophic factor) pamwe neBDNF yakawanda-inogadzirisa mapuroteni anokosha pakudzidza uye kuyeuka. Kuenzanisa pakati peJ-147 (1146963-51-0) powder uye zvakagadziriswa mu scopolamine model yakaratidza kuti kunyange zvazvo mapurisa maviri akafanana nekudzikinura nguva shoma kwenguva refu, J-147 powder yakanga iri nani pakununura mamiriro ekumusoro uye kusanganiswa kweiviri yakashanda zvakanakisisa nokuda kwenyaya nemakakungwa.

Mamwe mirayiridzo

Chirwere cheAlzheimer chirwere chepfungwa chinopfuurira mberi, chave chichionekwa sechitatu chekutungamirira kwekufa muUnited States uye chinokanganisa mamiriyoni mashanu eMelika. Ndicho chikonzero chinowanzokonzera demoenti kune vakwegura vakuru, maererano neNational Institutes of Health. Kunyange zvazvo mishonga yakawanda yakagadzirwa mumakore akapfuura e20 inotarisirwa kuti amyloid plaque igare muuropi (iyo inoratidza chiratidzo chechirwere), vashomanana vakaonekwa kuti vanobudirira muchechi.

"Kunyange zvazvo mishonga yakawanda yakagadzirwa mumakore ekupedzisira e20 inotarisirwa kuti majoi amyloid agone muuropi (iyo inoratidza chiratidzo chechirwere), hapana ane uchapupu hunoshanda muchechi," anodaro Schubert, mukuru munyori wekudzidza.

Makore anoverengeka adarika, Schubert nevamwe vake vakatanga kuswedera pakurapwa kwechirwere kubva kune imwe nzvimbo. Panzvimbo pekutsvaga zvinyorwa zvebazi, tebhu yakasarudza kusvika zero pane chikuru chinokonzerwa nehutano hwehutano. Kushandisa sero-based screens maererano nehutano hwehutano hunosangana nezera rekare, vakagadzira J 147 (1146963-51-0) powder.

Pamberi pacho, boka racho rakaona kuti J-147 powder inogona kudzivirira uye kunyange kugadzirisa kurasikirwa kwemazwi uye chirwere cheAlzheimer muzvipembenene zvine ruzivo rworudzi rwakagarwa rweAlzheimer's, rinowanzoshandiswa mumutsetse wemufananidzo. Zvisinei, chimiro chechirwere chacho chinongowanikwa chete ne1 muzana yezviitiko zveAlzheimer. Kune mumwe munhu wose, kukwegura ndiyo inonyanya kukosha, anodaro Schubert. Dare racho raida kutsvaga migumisiro yevhiringi vezvinodhaka pamhando yeveve dzinokurumidza kurarama uye dzinova nehuwandu hwekuora mwoyo kwechokuita zvakanyanya kufanana nehutano hwehutano hwevanhu.

J 147 Mvura Yakakosha

Min order 10grams.
Inobvunza pamusoro pezvakawanda (mukati 1kg) inogona kutumirwa mumaawa e12 mushure mekubhadhara.
Kuti uve mukuru (mukati 1kg) inogona kutumirwa muC3 kushanda kwemashure mushure mekubhadhara.

Raw J 147 powder Marketing

Kuti igoverwe mune ramangwana riri mberi.


Nzira yekutenga J 147 poda kubva kuAASraw

1.Kutaurirana nesu ne email yedu mvumo yekubvunzurudza, kana kuti inotenga skypeMutariri wevashandi (CSR).
2.Kutipa isu yakabvunzwa nekero.
3.Our CSR ichakupa iyo quotation, nguva yekubhadhara, nhamba yekutsvaga, nzira yekuendesa uye inofungidzirwa zuva rekuuya (ETA).
4.Payment yakaitwa uye zvigadzirwa zvichaendeswa mumaawa e12 (Kurongeka mukati me10kg).
5.Goods inogamuchira uye inopa mhinduro.


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COA

HNMR

Raw J-147 powder (1146963-51-0) hplc = 98% | AASraw SARMS powder

Recipes

J 147 Raw Powder Recipes:

Kubvunzurudza Mutengi wedu Mumiririri (CSR) nezvemashoko, nekuda kwako.

References & chigadzirwa mhizha

J-147 Powder Gwaro Rinotenga Kutenga uye Kudzokorora

Mishonga yekuongororwa J147 (1146963-51-0) Kurwara kweAlzheimer