Tauroursodeoxycholic asidhi (TUDCA) Powder (14605-22-2) hplc≥98% | AASraw
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Tauroursodeoxycholic acid (TUDCA) Poda (14605-22-2)

Rating: SKU: 14605-22-2. Category:

AASraw iri pamwe neyekushongedza uye kugona kugadzira kubva giramu kusvika kuwanda kurongeka kweTauroursodeoxycholic acid (TUDCA) Powder (14605-22-2), pasi peCGMP mutemo uye inotevedza yemhando yekudzora system.

Product Description

 

Tauroursodeoxycholic acid (TUDCA) Powder (14605-22-2) vhidhiyo

 

 


 

Tauroursodeoxycholic asidhi (TUDCA) Powder (14605-22-2) Specification:

Chemical Kuumbwa: Product Name: Tauroursodeoxycholic acid (TUDCA)
Cas.: 14605-22-2
Molecular Formula: C26H45NO6S
Molecular Weight: 499.7
Synonyms:Tauroursodeoxycholic acid, TUDCA, Tauroursodeoxycholate, Taurolite
Kuchengetedza: Chengetedza pa -20 ° C kure nechiedza uye unyoro.
Zvinyorwa (COA & HPLC nezvimwewo): Inowanikwa

 

Tauroursodeoxycholic asidhi (TUDCA) Powder (14605-22-2) Dnhoroondo:

Chinese mushonga wakashandisa mhuka bile kwemazana emakore semushonga kurapa "kupisa" zvirwere. Yakanga ichishandiswa kusunungura maspasms, kudzikisa kupisa muviri, uye kugadzirisa kunaka kwekuona. Bile inogadzirwa zvakasarudzika kuburikidza necholesterol, inosanganisira macomputer anosanganisira taurochenodeoxycholic acid, ursodeoxycholic acid, uye chenodeoxycholic acid. Zvisinei, UDCA neTUDCA zvakatanga kugadzirwa muna 1954 muJapan.

Tauroursodeoxycholic acid poda ndeye bile acid taurine conjugate yakatorwa kubva ku ursoodeoxycholic acid. Iine basa seyemetabolite yemunhu, inorwisa-kuzvimba mumiririri, neuroprotective mumiririri, apoptosis inhibitor, cardioprotective mumiriri uye pfupa rekuchengetedza mumiriri. Inobva kune ursodeoxycholic acid. Iyo conjugate acid ye tauroursodeoxycholate.

Tauroursodeoxycholic Acid (TUDCA) rubatsiro rwechiropa rwunounzwa sekuwedzera neThermoLife muchigadzirwa chavo Chiropa Chakareba. Inotaridzika senge yakanaka sosi yekudzivirira cholestasis, imwe yenjodzi huru ine 17 alkylated steroids. Tauroursodeoxycholic Acid (TUDCA) ndeye ambiphilic bile acid. Iyo ndiyo taurine conjugate fomu ye ursodeoxycholic acid (UDCA). Vanhu vanowanikwa vaine huwandu hweTUDCA. Zvisinei, mabheya ane huwandu hwakawanda hweTUDCA mune yavo bile. TUDCA iri kudzora apoptotic mhedzisiro, kubatsira nemoyo basa, chirwere cheHuntington, Chirwere chaPasinson, uye sitiroko. Munguva pfupi yapfuura, TUDCA yakawanikwa iine zvinodzivirira muziso, kunyanya zvine chekuita neretinal degenerative kusagadzikana.

 

Dheuteronomio:

  • Oveson BC, Iwase T, Hackett SF, Lee SY, Usui S, Sedlak TW, Snyder SH, Campochiaro PA, Sung JU (2011). "Zvinoumba bile, bilirubin uye TUDCA, zvinodzivirira kubva kune oxidative kusagadzikana-kunokonzeresa kuora kwetsvo". J. Neurochem. 116 (1): 144–153. doi: 10.1111 / j.1471-4159.2010.07092.x. PMC 4083853. PMID 21054389.
  • Duan, WJ, Zhang, FK, Ou XJ, Zhang, T, Wang, XM, Wang, Y, Cui, Y, Zhao, XY, Jia, JD (2011). "[Iwo makiriniki profiles ekutanga biliary cirrhosis ine suboptimal biochemical mhinduro kune ursodeoxycholic acid]". Zhonghua Gan Zang Bing Za Zhi. 19 (2): 118–120. doi: 10.3760 / cma.j.issn.1007-3418.2011.02.011 (isingashandi 2019-08-20). PMID 21492515.
  • Woo SJ, Kim JH, Yu HG (2010). "Ursodeoxycholic acid uye tauroursodeoxycholic acid inodzvinyirira choroidal neovascularization mune yemhando-yakarapwa gonzo remhando". J Ocul Pharmacol Ther. 26 (3): 223–229. doi: 10.1089 / jop.2010.0012. PMID 20565307.