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Trilostane Powder (13647-35-3)

Rating: SKU: 13647-35-3. Category:

AASraw iri pamwe neyekushongedza uye kugona kugadzira kubva giramu kusvika kuhuwandu hweTrostostane Powder (13647-35-3), pasi peCGMP mutemo uye trackable yemhando yekudzora system.

Product Description

Trilostane Powder (13647-35-3) vhidhiyo


Trilostane Powder (13647-35-3) Specification:

Chemical Kuumbwa: Product Name: Trilostane
Cas.: 13647-35-3
Molecular Formula: C20H27NO3
Molecular Weight: 329.43
Standard: In-house
Kuchengetedza: Dry, rima uye pa 0 - 4 C kwenguva pfupi (mazuva kusvika mavhiki) kana -20 C kwenguva refu (mwedzi kusvika kumakore).
Zvinyorwa (COA & HPLC nezvimwewo): Available

Trilostane Powder (13647-35-3) Dnhoroondo:

Trilostane poda inhibitor ye3β-hydroxysteroid dehydrogenase inoshandiswa pakurapa kweCushing's syndrome uye chepfungwa hyperaldosteronism. Aya ndiwo matambudziko maviri apa kuwanda kweiyo corticosteroid mahormone inogadzirwa mumuviri. Corticosteroids yakakosha kuti muviri ugone kushandisa macarbohydrate, mafuta nemapuroteni uye nemhinduro yakajairwa yekunetseka. Izvo zvinodikanwa zvakare kuitira kudzora kwemunyu uye chiyero chemvura mumuviri. Trilostane poda inobatsira kudzivirira kugadzirwa kwe corticosteroids, kudzora zviratidzo zvinosangana neiyi kusagadzikana.

Trilostane poda inogona zvakare kubatsira pakurapwa kwegomarara repazamu radzokerazve mune vakadzi vakapfuura nekuenda kumwedzi.

Ichangobvumidzwa muna2008 kurapwa kwechirwere cheCushing (hyperandrenocorticism) imbwa. Ndiwo wekutanga mushonga unobvumidzwa kubata zvese pituitary- uye adrenal-inomira Cushing's imbwa. Uyu mushonga wekunyorerwa unoshanda nekumisa kugadzirwa kwe cortisol mu adrenal glands.

Dheuteronomio:

  • 1: Midence JN, Drobatz KJ, Hess RS. Cortisol Concentrations mune Idzo dzakarongeka Imbwa neHyperadrenocorticism Yakaitirwa naTrilostane. J Vet Intern Med. 2015 Nov; 29 (6): 1529-33. doi: 10.1111 / jvim.13615. Epub 2015 Sep 16. PubMed PMID: 26374943.
  • 2: Fracassi F, Corradini S, Floriano D, Boari A, Aste G, Pietra M, Bergamini PF, Dondi F. Practostic zvinhu zvekupona imbwa dzine pituitary-based hypercortisolism yakarapwa ne trilostane. Vet Rec. 2015 Jan 10; 176 (2): 49. doi: 10.1136 / vr.102546. Epub 2014 Aug 28. PubMed PMID: 25170036.
  • 3: Bonadio CM, Feldman EC, Cohen TA, Kass PH. Kufananidza kwe adrenocorticotropic hormone kukurudzira miedzo yakatanga 2 pamwe neawa mana mushure mekutora kwetrostostane imbwa dzinowanzoitika hyperadrenocorticism. J Vet Intern Med. 4 Jul-Aug; 2014 (28): 4-1239. doi: 43 / jvim.10.1111. Epub 12357 Chivabvu 2014. PubMed PMID: 26.

KUGADZIRIRA UYE KUDZIDZA:

Ichi Chinyorwa Kutengeswa Kwekutsvagisa Chete Chete. Mitemo Yekutengesa Nyorera. Kwete Yekushandiswa Kwevanhu, kana Kurapa, Veterinary, kana Kushandisa Kweimba.


COA

HNMR

References & chigadzirwa mhizha