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Cortexolone 17α-propionate powder

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4.50 kupererwa ne 5 maererano ne 2 kasitoma ratings
SKU: 19608-29-8. Category:

MUTSVENE unobatanidzwa uye unogadzira zvigadzirwa kubva kugiramu kusvika pakukura kwe Cortexolone 17A-propionate powder (19608-29-8), pasi peCGMP mutemo uye trackable quality control system.

Product Description

Cortexolone 17α-propionate powder video


Cortexolone 17α-propionate powder Basic Characters

Name: Cortexolone 17α-propionate powder
CAS: 19608-29-8
Molecular Formula: C24H34O5
Molecular Weight: 402.52
Melt Point:
Storage Temp: Room Temperature Temperature
Color: Muchena kusvika pachena-pfu pfupa yeupfu


Cortexolone 17α-propionate cycle

Mazita

CAS: 19608-29-8
Kemikari Mazita: cortexolone-17α-propionate,
Mamwe Mazita: CB-03-01, Winlevi powder, Breezula powder, 11-deoxycortisol 17α-propionate, Cortexolone 17α-propionate powder

Cortexolone 17α-propionate Usage

Cortexolone 17A-propionate inoshandiswa steroidal antiandrogen - kunyanya, anrogen anorgen receptor - iyo iri pasi pekusimbiswa neCassiopea uye Intrepid Therapeutics kuti ishandiswe semishonga yepichepi mukurapa mamiriro ezvinhu anonzi androgen-kusanganisira acne vulgaris uye androgenic alopecia (murume-pattern kuputsika kwemvere).

Ndeipi iyo inonzi Cortexolone 17α-propionate

Cortexolone 17A-propionate 1% kamu, mushonga mutsva unorwisa antirogenrogen yepamusoro-soro wehutachi vulgaris. Mutevedzeri wechikwata anonzi randomized, double-blind comparing study vs. placebo uye tretinoin 0 · 05% kamu.

MARARAMIRO

Acne vulgaris chirwere chechikwata chechipiri chinogadziriswa umo inonzi androgens inobatsira kutanga kwayo nekushingaira. Kushandiswa kwe antiandrogen naizvozvo kunogona kushanda; zvisinei, antiandrogens yekushandiswa kwemashoko emitambo haisipo pamusika. Cortexolone 17A-propionate ichinhu chitsva chinonzi antiandrogen chinogona kushandiswa muzvinyorwa zvinopisa.

ZVINANGWA

Kuongorora kuchengetedza uye hutano hwehutano hweCortexolone 17A-propionate 1% kamu muAcne vulgaris kana uchienzaniswa ne placebo uye neTretinoin 0 · 05% kamu.

METHODS

Vane makumi manomwe nemanomwe vane chiso chavo vakawana 2-3 maererano neInvestigator's Global Assessment (IGA) yakashandurwa kuti iwane placebo cream (n = 15), kana Cortexolone 17A-propionate 1% cream (n = 30), kana tretinoin 0 · 05 % kamufa (n = 32) kamwe chete pazuva pamubhedha wevhiki dze8. Kushanda kwehutano kwakashandurwa masvondo ose e2 kusanganisira chiremera chenguva yese (TLC), kupisa kwechiremera kuverengwa (ILC), acne severity index (ASI) uye IGA. Kuchengetedzwa kwekuchengetedza kwakabatanidza nharaunda yekutsamwa kwemahara, kuongororwa kwebhakato, kuongorora kwemuviri, zviratidzo zvinokosha nekunyora kwezviitiko zvakashata.

RESULTS

CB-03-01-cream yakagadziriswa zvakanaka, uye yaive yakakosha kupfuura placebo pamusoro peTLC (P = 0 · 0017), ILC (P = 0 · 0134) uye ASI (P = 0 · 0090), uyewo kuchipatara zvinobudirira zvikuru kupfuura kufananidza. Chigadzirwa chacho chakakonzera kukurumidza kukurumidza kwe50% kuvandudzwa mune zvose zvataurwa pamusoro apa. CB-03-01

CONCLUSIONS

Ichi chidzidzo chekutsvaga chinotsigira chikonzero chekushandiswa kwemashoko anonzi antiandrogens mukurapa acne vulgaris. Cortexolone 17A-propionate 1% kamu cream inofananidzwa yakakodzana nehuwandu hwean antiandrogen yakanaka yekushandiswa kwemashoko.

Iyo Cortexolone 17A-propionate inoshanda sei

Cortexolone 17A-propionate (CAS 19608-29-8), kana 11-deoxycortisol 17α-propionate, inoshandiswa steroidal antiandrogen - kunyanya, anopesana neaorrogen receptor - iyo iri pasi pekusimbiswa neCassiopea uye Intrepid Therapeutics kuti ishandiswe semishonga yepicopic in kurapwa kwemamiriro ezvinhu a androgen-anogadzikana kusanganisira acne vulgaris uye androgenic alopecia (kurasikirwa nevhudzi-bvudzi). Ndiyo C17α propionate ester ya 11-deoxycortisol (cortexolone); C17A esters ye11-deoxycortisol yakanga isingatarisirwi kuti ine nhaka ye antiandrogen, uye cortexolone 17α-propionate yakasarudzwa kuti ibudirire zvichienderana nehuwandu hwehuwandu hwezvinodhaka.

Mumakonzo, mishonga iyi yakawanikwa iine simba yakasimba yepano antiandrogen, asi isingabatsiri systemic antiandrogen iyo inotungamirirwa kuburikidza nehutachiwana hutachiona. Mukuwedzera, cortexolone 17A-propionate haisi progonadotropic, inoratidza kuti iri kusarudzwa kamwechete. Mune chimiro chemhuka, chironga chemusoro chechirwere chakanga chiri chikuru kune cheprogesterone, flutamide, uye mari yemari uye yakanga yakaenzana neyeyproterone acetate.

Mutyairi wechipatara mutsva mu 2011 yevarume vaibatwa netikitikiti cortexolone 17α-propionate 1% kamu yeakoni yakawana kuti mishonga yakanyatsorambidzwa uye yakaderedza zvikuru zviratidzo zvepine. Uyezve, kubudirira kwacho kwaive kwakakura kudarika kweyomuenzanisi anoshanda, tretinoin 0.05% cream. SezvaA2017, mushonga uyu uri muchitsauko III kliniki miedzo ye acne vulgaris uye chirongwa chechipiri chemakiriniki ye androgenic alopecia.

yambiro

Cortexolone 17α-proprionate, Breezula powder mu polymorphic maitiro ayo: mhuri yekutanga yepa patent, inopera muUnited States mu2022 / 23 uye mu 2022 kune dzimwe nyika, inoshandisa kushandiswa kwechiremba kwekemukari yekurapa acne, alopecia uye zvimwe zvirwere; mhuri yechipiri yepavhangeri inosanganisa maitiro ose anozivikanwa e-crystalline eAAPI, maumbirwo ane anopa API imwechete uye kushandiswa kwezvokurapa kwakabatana mukurapa mashekeri, AGA nezvimwe zvirwere: mhuri iyi yepamutemo yakatobudiswa muUnited States, Europe, Canada, Japan uye dzimwe nyika, dzichapera mu2030 muUnited States uye 2028 kune dzimwe nyika.Breezula powder

Cortexolone 17α-propionate Raw Powder

Min order 10grams.
Inobvunza pamusoro pezvakawanda (mukati 1kg) inogona kutumirwa mumaawa e12 mushure mekubhadhara.
Kuti uwedzere kurongeka kunogona kutumirwa mumazuva ekushanda kwe3 mushure mekubhadhara.

Cortexolone 17A-propionate Raw Powder Recipes

Kubvunzurudza Mutengi wedu Mumiririri (CSR) nezvemashoko, nekuda kwekutaura kwako.Winlevi powder

Cortexolone 17α-propionate Marketing

Kuti igoverwe mune ramangwana riri mberi.

Ko Cortexolone 17A-propionate Iine Mhinduro Dzakashata

Cortexolone 17A-propionate inoshandiswa steroidal-ester, inoparadzanisa uyerogen-antagonist, inopiwa basa risiri rinopisa simba, iro rinoratidzika rakakodzera zvakakodzera kurapa acne vulgaris. CB-03-01 inoshanda pamunhu we-androgen-receptor pasina kuvhara 5α-kuderedza mucheche. Steroid iri nyore kupinda mukati meganda revanhu uye inokurumidza kugadziriswa kuti isunungure mubereki cortexolone iyo isingashandisi systemic effects. Zvinonyanya kukosha, kuti uwane ushamwari, hazvina kuratidza chero mamiriro ezvinhu emunharaunda kana sitiroid madhara.


Nzira yekutenga Cortexolone 17A-propionate powder kubva kuAASraw

1.Kutaurirana nesu ne email yedu mvumo yekubvunzurudza, kana kuti inotenga skypeMutariri wevashandi (CSR).
2.Kutipa isu yakabvunzwa nekero.
3.Our CSR ichakupa iyo quotation, nguva yekubhadhara, nhamba yekutsvaga, nzira yekuendesa uye inofungidzirwa zuva rekuuya (ETA).
4.Payment yakaitwa uye zvigadzirwa zvichaendeswa mumaawa e12 (Kurongeka mukati me10kg).
5.Goods inogamuchira uye inopa mhinduro.


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COA

HNMR

Recipes

Cortexolone 17A-propionate Raw Powder Recipes:

Kubvunzurudza Mutengi wedu Mumiririri (CSR) nezvemashoko, nekuda kwekutaura kwako.Winlevi powder

References & chigadzirwa mhizha

Kurapa Kwemusoro Kunobatsira Vanhu: Cortexolone 17α-propionate powder (CB-03-01)